Discover how experts from CAS, LaJolla Institute for Immunology, and Avidity Biosciences are exploring the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more. The recap and slides are here.
Learn how chemistry powers space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.
Discover how Ozempic, Wegovy, and Mounjaro are part of a new class of semaglutides (GLP-1 receptor agonists) that help treat obesity and diabetes by regulating blood sugar and appetite.
Discover the latest in anti-aging treatment strategies to promote health and longevity. Uncover the latest research on stem cell therapies, hyaluronic acid, senolytics, gene therapy, and a pipeline analysis of ongoing clinical trials in our latest article.
Learn how to overcome PEG immunogenicity, a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. This article reviews the current state-of-the-art in addressing PEG immunogenicity, from elucidating the factors that influence anti-PEG antibody production to developing novel drug vehicles or optimizing administration and posology.
The gut microbiome is a complex ecosystem of trillions of bacteria that live in our digestive tracts with health benefits like immunity, improved mental health, and therapeutic options. In recent years, there has been a growing interest in the potential of microbiome therapies to treat a variety of diseases. As our understanding of the gut microbiome continues to grow, we can expect to see more advances in microbiome therapies in the years to come.
As the leading cause of drug-related deaths, fentanyl has become a public health crisis, but new breakthroughs in developing safer pain medications, reducing side effects, and developing a vaccine may reduce future deaths.
Stay ahead of the curve with the latest in emerging science and cutting-edge research that is accelerating the landscape of innovation. From new discoveries in synthetic biology to breakthroughs in sustainable energy, these are the breakthroughs that will reshape 2023. The experts at CAS reveal unique analysis and emerging trends from their landscape view of the world’s science.
Learn about the basics of click chemistry and bioorthogonal chemistry that was recently awarded the 2022 Nobel Prize in Chemistry. Read about emerging trends, insights on publication trends, and future applications of bioorthogonal chemistry.
NASA’s Artemis Program has also focused attention on topics such as food safety, reliability, and nutrition in space. This blog touches on novel approaches to these problems like 3D printed space food, the use of microbes to produce nutrients, and closed-loop space farming.
With recent headlines on monkeypox, learn more about the research landscape, scientific profiles, and currently available therapies. A deeper understanding of the published science enables clarity and insight on this emerging news story.
Gut microbiota, gut flora, or microbiome are the microorganisms that live in the digestive tracts of humans and other animals. While some bacteria are associated with disease, others are particularly important for many aspects of health and mental health.
Newly developed microfluidic fabrication technology addresses the clinical need for scalable, precise, and reproducible solutions for vaccine production.
Discover how catalysts and catalysis have transformed our world, from ancient times to modern sustainability. Learn about the latest research trends and innovations in this fascinating field of chemistry.
With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.
Learn how mRNA vaccines, which have revolutionized the fight against COVID-19, can also be used to treat cancer by harnessing the power of the immune system.
Supercapacitors vs. batteries: Is graphene the key to unlocking their full potential? Learn how graphene-based supercapacitor technologies are ready for real-world applications and what challenges they face.
Learn about the latest advancements in lithium-ion battery recycling technology in this article. Discover a new approach for direct recycling that could make it possible to repair and reuse depleted batteries at a lower cost. Understand the challenges still facing the industry and the potential impact on the future of battery recycling.
Discover the innovative applications of biomedical 3D printing, starting with from a short history of the technology, all the way to the latest trends of 3D printing in healthcare.
Understand the environmental threat of microplastics by exploring its impact through resources such as the 2022 WHO report on dietary and inhalation exposure to microplastics, and microplastics publications trends.
Learn more about lipid nanoparticles, their origin, role in COVID vaccines, and future applications. This overviews emerging trends and insights on publications, milestones, and future applications in vaccines, drug delivery, and non-therapeutic applications like agro-chemistry, cosmetics, and food science.
Find out how companies improve their prediction accuracy, obtain Breakthrough Technology Status and shorten the development and review time of new drugs by leveraging CAS advanced machine learning methods.
This blog details the recently published CAS indicator of drug innovation based on the structural novelty of new molecular entities (NMEs) which may better assess innovativeness of new drugs.
It is estimated that one in five human cancers involve RAS mutations. Although once considered undruggable, this blog looks at recent advances in RAS inhibitors and emerging therapies.
The COVID pandemic revealed deficiencies in mask development and production. Innovation will be crucial in slowing the spread of new variants of the virus. There are many factors that can be improved for masks, and this article focuses on the emerging science of improving filtration and microorganism removal.
As COVID-19 cases rise again worldwide, the Omicron subvariant BA.5 is currently the dominant strain. This blog explores some key mutations that increase transmission, evade protective antibodies, and increase the rate of (re)infection.
Molecular glues have been used to uncover new therapeutic agents. Because of their targeted protein degradation that holds them together, these glues have exciting potential in uncovering new drugs to fight cancer, immune diseases, and more.
We are in the midst of a therapeutic revolution, according to the authors of a recent review article in Frontiers in Bioengineering and Biotechnology. They were commenting on the rapid expansion of RNA therapeutics in modern research and clinical development, driven in part by interest in RNA COVID-19 vaccines in the ongoing SARS-CoV-2 pandemic.
A literature search in the CAS Content Collection provides useful insights into recent and ongoing intensive research and development into green hydrogen production, storage, and utilization in fuel cells. The trends in publications suggest that hydrogen storage and fuel cells are becoming technologically mature whereas, green hydrogen production is still at an exploratory stage. Read the blog to learn more.
Preliminary study of the Omicron variant indicates that it has evolved significantly from the original version of the virus first identified in China in 2019, which means there is an increased likelihood that it could reinfect those who have already had COVID-19 or evade the immunity generated by the current first generation of vaccines. Such a variant could drastically set back the global pandemic recovery, resulting in staggering societal and economic impacts.
In support of ongoing research efforts to identify additional drugs for COVID-19, a team of CAS scientists analyzed published scientific information and created a comprehensive report focusing on proteins involved in COVID-19 and potential corresponding drug candidates. Learn how CAS has committed to leveraging their assets and capabilities to support the fight against COVID-19.
